Pore size alone does not matter when biological nanopores act as sugar chain biosensors

Protein nanopores are present in cell membranes and act as biological gateways. This means that they can also be used for the detection of specific bioactive molecular chains, like sugar chains, such as molecules from the glycosaminoglycan family. The latter are responsible for key interactions at the cellular level. They typically mediate interactions with cell surfaces or with proteins, resulting in the activiation of physiological and pathological effects in embryonic development, cell growth and differentiation, inflammatory response, tumour growth and microbial infection. The use of such nanopores as biosensors requires to fully understand the intricate mechanisms occurring as sugar chains pass through them.

Pore size alone does not matter when biological nanopores act as sugar chain biosensors

Protein nanopores are present in cell membranes and act as biological gateways. This means that they can also be used for the detection of specific bioactive molecular chains, like sugar chains, ...

Thu 8 Nov 18 from Phys.org

Pore size alone does not matter when biological nanopores act as sugar chain biosensors, Thu 8 Nov 18 from ScienceDaily

Pore size alone does not matter when biological nanopores act as sugar chain biosensors, Thu 8 Nov 18 from Eurekalert

Study Reveals Core Criteria Determining Efficiency of Two Types of Nanopores in Detecting Sugar Chains

Protein nanopores are found in cell membranes and serve as biological gateways. This means that they can also be used for detecting specific bioactive molecular chains, like sugar chains, such ...

Fri 9 Nov 18 from AZoNano

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