More Cancer Mutations, Better Immunotherapy Outcomes

A large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has found that the mutational load of a tumor may be a useful way to predict a response to checkpoint-inhibitor immunotherapy across different types of cancer. In their paper published in the journal Nature Genetics, the group describes their study of over 1,500 patients with advanced cancer who had undergone checkpoint-inhibitor immunotherapy, and what they found.

More Cancer Mutations, Better Immunotherapy Outcomes

Immune checkpoint inhibitors are generally most effective against tumors with more genetic mutations, according to a new study, although the relationship isn't true for all cancers.

Tue 15 Jan 19 from The Scientist

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

A large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has found that the mutational load of a tumor may ...

Tue 15 Jan 19 from Medical Xpress

Uncovering more options in cancer immunotherapy

To make it possible for cancer immunotherapy to help more people, think small.

Thu 10 Jan 19 from Medical Xpress

Drug sponge could minimize side effects of cancer treatment

With the help of sponges inserted in the bloodstream to absorb excess drugs, doctors are hoping to prevent the dangerous side effects of toxic chemotherapy agents or even deliver higher doses ...

Wed 9 Jan 19 from Phys.org

Drug sponge could minimize side effects of cancer treatment, Wed 9 Jan 19 from ScienceDaily

Drug sponge could minimize side effects of cancer treatment, Wed 9 Jan 19 from Eurekalert

New device could reduce toxic chemotherapy side effects?

Chemically coated, 3-D printed cylinder removes a common chemotherapy drug from the bloodstream??

Mon 14 Jan 19 from CandEN

Capturing Chemotherapy Drugs Before They Can Cause Side Effects

NewsIf doctors could remove excess chemotherapy drugs from a patient's bloodstream after the medicines have done their job, they might reduce side effects such as hair loss and nausea.Contributed ...

Thu 10 Jan 19 from Laboratory Equipment

Capturing chemotherapy drugs before they can cause side effects, Wed 9 Jan 19 from Eurekalert

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