Scientists discover the basics of how pressure-sensing Piezo proteins work

A team of scientists from Weill Cornell Medicine and The Rockefeller University has illuminated the basic mechanism of Piezo proteins, which function as sensors in the body for mechanical stimuli such as touch, bladder fullness, and blood pressure. The discovery is a feat of basic science that also opens up many new paths of investigation into the roles of Piezo proteins in human diseases and potential new therapeutic strategies.

Scientists discover the basics of how pressure-sensing Piezo proteins work

A team of scientists from Weill Cornell Medicine and The Rockefeller University has illuminated the basic mechanism of Piezo proteins, which function as sensors in the body for mechanical stimuli ...

Wed 21 Aug 19 from Phys.org

Scientists discover the basics of how pressure-sensing Piezo proteins work, Wed 21 Aug 19 from ScienceDaily

Scientists discover the basics of how pressure-sensing Piezo proteins work, Wed 21 Aug 19 from Eurekalert

A mechanism for touch

Nature, Published online: 21 August 2019; doi:10.1038/d41586-019-02454-2Piezo proteins mediate the sense of touch. A near-complete structure of one such protein has been obtained, ...

Wed 21 Aug 19 from Nature News

Force-induced conformational changes in PIEZO1

Nature, Published online: 21 August 2019; doi:10.1038/s41586-019-1499-2Cryo-electron microscopy and high-speed atomic force microscopy reveal that PIEZO1 can reversibly deform ...

Wed 21 Aug 19 from Nature News

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