Free-electron lasers reveal detailed architecture of proteins

(Phys.org) -- In the centennial year of Max von Laue’s discovery that X-ray diffraction can be used to unravel the atomic architecture of molecules, a new approach to the determination of high-resolution structures has been demonstrated. An international team of researchers has analyzed tiny protein crystals using short pulses of X-ray light from the world’s first hard X-ray free-electron laser, the US Department of Energy’s 300 million dollar Linac Coherent Light Source at Stanford. The study demonstrates the immense potential of free-electron lasers for obtaining the structures of macromolecules from tiny crystals when illuminated with the blazing intensity of the ultrashort free-electron laser X-ray pulses, even though the crystals are destroyed in the process. In the current study, their structural analysis reveals details with a spatial resolution of 0.2 millionth of a millimeter.

Free-electron lasers reveal detailed architecture of proteins

(Phys.org) -- In the centennial year of Max von Laue’s discovery that X-ray diffraction can be used to unravel the atomic architecture of molecules, a new approach to the determination ...

Fri 1 Jun 12 from Phys.org

Free-electron lasers reveal detailed architecture of proteins, Mon 4 Jun 12 from R&D Mag

Free-electron lasers reveal detailed architecture of proteins, Thu 31 May 12 from ScienceDaily

Free-electron lasers reveal detailed architecture of proteins, Thu 31 May 12 from AlphaGalileo

SLAC X-ray laser used to probe biomolecules to individual atoms

An international team led by SLAC National Accelerator Laboratory has proved how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes ...

Thu 31 May 12 from Phys.org

X-ray Laser Resolves Atomic Structure of Biomolecules

An international team, led by the U.S. Department of Energy's SLAC National Accelerator Laboratory and including members from Arizona State University, has shown how the world's most powerful ...

Fri 1 Jun 12 from Newswise

X-ray laser resolves atomic structure of biomolecules, Fri 1 Jun 12 from Eurekalert

X-ray laser probes biomolecules to individual atoms

Scientists have demonstrated how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes helped to pioneer critical new investigative ...

Thu 31 May 12 from ScienceDaily

X-ray laser probes biomolecules to individual atoms, Thu 31 May 12 from R&D Mag

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